Default: The same plot(s) that are open at the outset of Career ModeĬertain factors, primarily the starting conditions such as monetary balance, are set upon beginning a new Sandbox game.Unlock with Research: Machines are made available with their respective Rooms, but all upgrades must be obtained by completing Research Projects.Unlock with Kudosh: Kudosh is used to unlock items that are unlocked that way in Career Mode, as well as Star Level rewards.All Unlocked: All available from the outset.Unlock with Research: Many basic rooms are available from the start, including all facilities, the rest must be obtained by completing Research Projects.All Junior: All staff for hire are lowest rank, with no qualifications.Medical Students: All Doctors and Nurses for hire are students with no qualifications.Default: Staff for hire can be any rank, with a range of qualifications.
Staff Development: Sets objectives primarily involving promoting and training staff, and maintaining their morale. Research & Training: Sets objectives primarily involving generating Research Points and training staff. Moneymaker: Sets objectives primarily involving income and Hospital Value. Cure & Expand: Sets objectives primarily involving Curing Patients, Cure Rate and Hospital Value. Cure Patients: Sets objectives primarily involving Curing Patients, Cure Rate and Reputation. Speedy Recovery: Illnesses found by the custom ambulances of Two Point County (and Speedy Recovery DLC). A Stitch in Time: Illnesses found around the temporal rift of Two Point County (and A Stitch In Time DLC). Culture Shock: Illnesses found in the East of Two Point County (and Culture Shock DLC). Off The Grid: Illnesses found in the West of Two Point County (and Off The Grid DLC). Close Encounters: Illnesses found in the South of Two Point County (and Close Encounters DLC). 
Pebberley Island: Illnesses found off the mainland of Two Point County (and Pebberley Island DLC).Bigfoot: Illnesses found in the Pointy Mountains (and Bigfoot DLC).All from the Start: All illnesses are active from the beginning.
Visible Symptoms Only: Only illnesses with visible symptoms are active. Hard: Illnesses that are hard to diagnose, with a lower chance of treatment success. Medium: Illnesses that are moderately challenging to diagnose and treat. Easy: Illnesses that are easy to diagnose, with a higher chance of treatment success. 
All over Time: Every illness will feature, with more difficult illnesses appearing as the hospital grows. Patient Arrival Rate: Defaults to x1.00, but can be specified from x0.25 to x2.00. Income Multiplier: Defaults to x1.00, but can be specified from x0.00 to x2.00. Kudosh: Starting amount, defaults to 100, but can be specified from K0 to K20,000. Name: Defaults to that of the hospital itself, but can be specified.
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